Membrane domain formation – a key factor for targeted intracellular drug delivery

Membrane domain formation – a key factor for targeted intracellular drug delivery

Protein molecules, toxins and viruses internalize into the cell via receptor-mediated endocytosis (RME) using specific proteins and lipids in the plasma membrane. The plasma membrane is a barrier for many pharmaceutical agents to enter into the cytoplasm of target cells. In the case of cancer cells,...

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Bibliographic Details
Main Authors: Dušan ePopov-Čeleketić, Paul M.P. van Bergen en Henegouwen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Physiology
Subjects:
EGFR
receptor clustering
Drug delivery
cancer therapy
membrane domain
Receptor mediated endocytosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00462/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00462/full

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