GAS6/AXL Axis Regulates Prostate Cancer Invasion, Proliferation, and Survival in the Bone Marrow Niche

Our recent studies have shown that annexin II, expressed on the cell surface of osteoblasts, plays an important role in the adhesion of hematopoietic stem cells (HSCs) to the endosteal niche. Similarly, prostate cancer (PCa) cells express the annexin II receptor and seem to use the stem cell niche...

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Main Authors: Yusuke Shiozawa, Elisabeth A. Pedersen, Lalit R. Patel, Anne M. Ziegler, Aaron M. Havens, Younghun Jung, Jingcheng Wang, Stephanie Zalucha, Robert D. Loberg, Kenneth J. Pienta, Russell S. Taichman
Format: Article
Language:English
Published: Elsevier 2010-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800910