Inferring pathway activity toward precise disease classification.

The advent of microarray technology has made it possible to classify disease states based on gene expression profiles of patients. Typically, marker genes are selected by measuring the power of their expression profiles to discriminate among patients of different disease states. However, expression-...

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Bibliographic Details
Main Authors: Eunjung Lee, Han-Yu Chuang, Jong-Won Kim, Trey Ideker, Doheon Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18989396/pdf/?tool=EBI