Acidic extracellular and intracellular pH modifies benzo[a]pyrene induced DNA damage and repair
Chronic inflammation creates an acidic microenvironment, which may play an important role in cancer development. To investigate how a low pH may change the cellular response to the environmental carcinogen benzo[a]pyrene (B[a]P), we exposed human pulmonary epithelial cells (A549) to non-toxic doses...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-06-01
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| Series: | Frontiers in Genetics |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/conf.fgene.2015.01.00002/full |