Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy

Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy

In cancer, the extracellular matrix is extensively remodeled during chronic inflammation, thus affecting cell transcription, differentiation, migration and cell-cell interactions. Matrix metalloproteinases can degrade the extracellular matrix of tumor tissues and take important roles in disease prog...

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Bibliographic Details
Main Authors: Minglong Liang, Jian Wang, Chuanjian Wu, Manman Wu, Jingping Hu, Jianfeng Dai, Hang Ruan, Sidong Xiong, Chunsheng Dong
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Translational Oncology
Subjects:
Colon cancer
Combination therapy
Cell proliferation
Matrix metalloproteinases
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321002138

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http://www.sciencedirect.com/science/article/pii/S1936523321002138

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