The Endocannabinoid System Activation as a Neural Network Desynchronizing Mediator for Seizure Suppression

The Endocannabinoid System Activation as a Neural Network Desynchronizing Mediator for Seizure Suppression

The understanding that hyper-excitability and hyper-synchronism in epilepsy are indissociably bound by a cause-consequence relation has only recently been challenged. Thus, therapeutic strategies for seizure suppression have often aimed at inhibiting excitatory circuits and/or activating inhibitory...

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Bibliographic Details
Main Authors: Daniel de Castro Medeiros, Vinícius Rosa Cota, Antonio Carlos P. Oliveira, Fabricio A. Moreira, Márcio Flávio Dutra Moraes
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
epilepsy
cannabinoid system
neural synchrony oscillations
deep brain electrical stimulation
network decoupling
pharmacological treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2020.603245/full

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https://www.frontiersin.org/articles/10.3389/fnbeh.2020.603245/full

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