Therapeutic Potential of Tauroursodeoxycholic Acid for the Treatment of Osteoporosis

Therapeutic Potential of Tauroursodeoxycholic Acid for the Treatment of Osteoporosis

Tauroursodeoxycholic acid (TUDCA) is a US FDA-approved hydrophilic bile acid for the treatment of chronic cholestatic liver disease. In the present study, we investigate the effects of TUDCA on the proliferation and differentiation of osteoblasts and its therapeutic effect on a mice model of osteopo...

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Bibliographic Details
Main Authors: Tae-Keun Ahn, Kyoung-Tae Kim, Hari Prasad Joshi, Kwang Hwan Park, Jae Won Kyung, Un-Yong Choi, Seil Sohn, Seung-Hun Sheen, Dong-Eun Shin, Soo-Hong Lee, In-Bo Han
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
osteoblast
osteoporosis
bone turnover biomarkers
matrix mineralization
bone histomorphometry
Online Access:https://www.mdpi.com/1422-0067/21/12/4274

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https://www.mdpi.com/1422-0067/21/12/4274

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