Effect of a Bone Morphogenetic Protein-2-derived peptide on the expression of tumor marker ZNF217 in osteoblasts and MCF-7 cells

Effect of a Bone Morphogenetic Protein-2-derived peptide on the expression of tumor marker ZNF217 in osteoblasts and MCF-7 cells

Zinc Finger Protein 217 (ZNF217), a transcription factor and oncogene product, has been found to dysregulate Bone Morphogenetic Protein (BMP) signaling and induce invasion in breast tumors. In this study, the effect of BMP-2 or an active BMP-2 peptide, AISMLYLDEN, on the expression of ZNF217, BMP4 a...

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Bibliographic Details
Main Authors: Aglaia Mantsou, Maria Pitou, Eleni Papachristou, Rigini M. Papi, Paraskevas Lamprou, Theodora Choli-Papadopoulou
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Bone Reports
Subjects:
Bone Morphogenetic Protein-2
Breast cancer
Osteogenic differentiation
CDK-inhibitor p21
Zinc Finger Protein 217
Online Access:http://www.sciencedirect.com/science/article/pii/S235218722100382X

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http://www.sciencedirect.com/science/article/pii/S235218722100382X

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