NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis

NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis

We investigate as yet an unidentified role of NOX1, a non-phagocytic isoform of the superoxide-generating NADPH oxidase, in immune responses using Nox1-knockout mice (Nox1-KO). The transcripts of NOX1 was expressed in lymphoid tissues, including the spleen, thymus, bone marrow, and inguinal lymphoid...

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Bibliographic Details
Main Authors: Misaki Matsumoto, Junjie Liu, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Xueqing Zhang, Masato Katsuyama, Masaya Matsuda, Takeshi Nabe, Katrin Schröder, Chihiro Yabe-Nishimura
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Pharmacological Sciences
Subjects:
NADPH oxidase
Reactive oxygen species
Arthritis
Endotoxin
LPS
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000104

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http://www.sciencedirect.com/science/article/pii/S1347861321000104

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