Augmentation of the anticancer activity of CYT997 in human prostate cancer by inhibiting Src activity

Abstract Background Abnormalities of tubulin polymerization and microtubule assembly are often seen in cancer, which make them very suitable targets for the development of therapeutic approach against rapidly dividing and aggressive cancer cells. CYT997 is a novel microtubule-disrupting agent with a...

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Bibliographic Details
Main Authors: Yong Teng, Yafei Cai, Wenhu Pi, Lixia Gao, Chloe Shay
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Hematology & Oncology
Subjects:
Src
Online Access:http://link.springer.com/article/10.1186/s13045-017-0485-0