Dilated thin-walled blood and lymphatic vessels in human endometrium: a potential role for VEGF-D in progestin-induced break-through bleeding.

Progestins provide safe, effective and cheap options for contraception as well as the treatment of a variety of gynaecological disorders. Episodes of irregular endometrial bleeding or breakthrough bleeding (BTB) are a major unwanted side effect of progestin treatment, such that BTB is the leading ca...

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Bibliographic Details
Main Authors: Jacqueline F Donoghue, C Jay McGavigan, Fiona L Lederman, Leonie M Cann, Lulu Fu, Eva Dimitriadis, Jane E Girling, Peter A W Rogers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3284580?pdf=render