Destruction of extracellular matrix proteoglycans is pervasive in simian retroviral neuroinfection

Disruption of the perineuronal matrix has been reported in human immunodeficiency virus (HIV) encephalitis. To better understand the extent of matrix disruption during lentiviral encephalitis, we characterized the extracellular matrix (ECM) damage in brains of 12 macaques infected with simian immuno...

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Bibliographic Details
Main Authors: Rafael Medina-Flores, Guoji Wang, Stephanie J Bissel, Michael Murphey-Corb, Clayton A Wiley
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Neurobiology of Disease
Subjects:
SIV
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104001044