Maturation of the mitochondrial redox response to profound asphyxia in fetal sheep.

Fetal susceptibility to hypoxic brain injury increases over the last third of gestation. This study examined the hypothesis that this is associated with impaired mitochondrial adaptation, as measured by more rapid oxidation of cytochrome oxidase (CytOx) during profound asphyxia.Chronically instrumen...

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Bibliographic Details
Main Authors: Paul P Drury, Laura Bennet, Lindsea C Booth, Joanne O Davidson, Guido Wassink, Alistair J Gunn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3376132?pdf=render