The Addition of a Synthetic LPS-Targeting Domain Improves Serum Stability While Maintaining Antimicrobial, Antibiofilm, and Cell Stimulating Properties of an Antimicrobial Peptide

The Addition of a Synthetic LPS-Targeting Domain Improves Serum Stability While Maintaining Antimicrobial, Antibiofilm, and Cell Stimulating Properties of an Antimicrobial Peptide

Multi-drug resistant (MDR) bacteria and their biofilms are a concern in veterinary and human medicine. Protegrin-1 (PG-1), a potent antimicrobial peptide (AMP) with antimicrobial and immunomodulatory properties, is considered a potential alternative for conventional antibiotics. AMPs are less stable...

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Bibliographic Details
Main Authors: Anna Maystrenko, Yulong Feng, Nadeem Akhtar, Julang Li
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
antimicrobial peptide
protegrin-1
stability
hybridization
biofilm
serum
Online Access:https://www.mdpi.com/2218-273X/10/7/1014

Internet

https://www.mdpi.com/2218-273X/10/7/1014

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