No G-Quadruplex Structures in the DNA of Parvovirus B19: Experimental Evidence versus Bioinformatic Predictions

No G-Quadruplex Structures in the DNA of Parvovirus B19: Experimental Evidence versus Bioinformatic Predictions

Parvovirus B19 (B19V), an ssDNA virus in the family Parvoviridae, is a human pathogenic virus, responsible for a wide range of clinical manifestations, still in need of effective and specific antivirals. DNA structures, including G-quadruplex (G4), have been recognised as relevant functional feature...

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Bibliographic Details
Main Authors: Gloria Bua, Daniele Tedesco, Ilaria Conti, Alessandro Reggiani, Manuela Bartolini, Giorgio Gallinella
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Viruses
Subjects:
parvovirus B19
G-quadruplex
bioinformatics
antivirals
BRACO-19
pyridostatin
Online Access:https://www.mdpi.com/1999-4915/12/9/935

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https://www.mdpi.com/1999-4915/12/9/935

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