Cancer Genomic Profiling in Colorectal Cancer: Current Challenges in Subtyping Colorectal Cancers Based on Somatic and Germline Variants
Colorectal cancer (CRC) is a heterogeneous disease caused by the accumulation of multistep genetic alterations under the influence of genomic instability. Different backgrounds of genomic instability, such as chromosomal instability, microsatellite instability, hypermutated-single nucleotide variant...
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Format: | Article |
Language: | English |
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The Japan Society of Coloproctology
2021-07-01
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Series: | Journal of the Anus, Rectum and Colon |
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Online Access: | https://www.jstage.jst.go.jp/article/jarc/5/3/5_2021-009/_pdf/-char/en |