Cancer Genomic Profiling in Colorectal Cancer: Current Challenges in Subtyping Colorectal Cancers Based on Somatic and Germline Variants

Colorectal cancer (CRC) is a heterogeneous disease caused by the accumulation of multistep genetic alterations under the influence of genomic instability. Different backgrounds of genomic instability, such as chromosomal instability, microsatellite instability, hypermutated-single nucleotide variant...

Full description

Bibliographic Details
Main Author: Takao Hinoi
Format: Article
Language:English
Published: The Japan Society of Coloproctology 2021-07-01
Series:Journal of the Anus, Rectum and Colon
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jarc/5/3/5_2021-009/_pdf/-char/en