Female bias in systemic lupus erythematosus is associated with the differential expression of X-linked Toll-like receptor 8

Female bias in systemic lupus erythematosus is associated with the differential expression of X-linked Toll-like receptor 8

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of anti-nuclear antibodies. SLE is one of many autoimmune disorders that have a strong gender bias, with 70-90% of SLE patients being female. Several explanations have been postulated to account for th...

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Bibliographic Details
Main Authors: Gabrielle eMcdonald, NIcholas eCabal, Augustin eVannier, Benjamin eUmiker, Raymund H Yin, Arturo V Orjalo, Hans E Johansson, Jin-Hwan eHan, Thereza eImanishi-Kari
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
Neutrophils
SLE
TLR8
X-inactivation
IFN-I
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00457/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00457/full

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