Comprehensive analysis of immune cell enrichment in the tumor microenvironment of head and neck squamous cell carcinoma

Abstract Head and neck squamous carcinoma (HNSCC) is highly infiltrated by immune cells, including tumor-infiltrating lymphocytes and myeloid lineage cells. In the tumor microenvironment, tumor cells orchestrate a highly immunosuppressive microenvironment by secreting immunosuppressive mediators, ex...

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Bibliographic Details
Main Authors: Ikko Mito, Hideyuki Takahashi, Reika Kawabata-Iwakawa, Shota Ida, Hiroe Tada, Kazuaki Chikamatsu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95718-9