Effect of (-)-∆9-tetrahydrocannabinoid on the hepatic redox state of mice

Effect of (-)-∆9-tetrahydrocannabinoid on the hepatic redox state of mice

(-)-∆9-Tetrahydrocannabinol (∆9-THC), a psychoactive component of marijuana, has been reported to induce oxidative damage in vivo and in vitro. In this study, we administered ∆9-THC to healthy C57BL/6J mice aged 15 weeks in order to determine its effect on hepatic redox state. Mice were divided into...

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Bibliographic Details
Main Authors: C.E. Pinto, E. Moura, M.P. Serrão, M.J. Martins, M.A. Vieira-Coelho
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2010-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
(-)-∆9-Tetrahydrocannabinol
Oxidative stress
Liver
Cannabinoid receptors
Cremophor EL®
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000400001&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000400001&lng=en&tlng=en

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