QbD Enabled Azacitidine Loaded Liposomal Nanoformulation and Its In Vitro Evaluation

Azacitidine (AZA), an inhibitor of DNA methyltransferase, is a commonly recognized drug used in clinical treatment for myelodysplastic syndrome and breast cancer. Due to higher aqueous solubility and negative log P of AZA causes poor cancer cell permeation and controlled release. The objective of th...

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Bibliographic Details
Main Authors: Prashant Kesharwani, Shadab Md, Nabil A. A. Alhakamy, Khaled M. M. Hosny, Anzarul Haque
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/13/2/250