Targeting Follistatin like 1 ameliorates liver fibrosis induced by carbon tetrachloride through TGF-β1-miR29a in mice

Targeting Follistatin like 1 ameliorates liver fibrosis induced by carbon tetrachloride through TGF-β1-miR29a in mice

Abstract Background Hepatic fibrosis is a pathological response of the liver to a variety of chronic stimuli. Hepatic stellate cells (HSCs) are the major source of myofibroblasts in the liver. Follistatin like 1 (Fstl1) is a secreted glycoprotein induced by transforming growth factor-β1 (TGF-β1). Ho...

Full description

Bibliographic Details
Main Authors: Xin-Yi Xu, Yan Du, Xue Liu, Yilin Ren, Yingying Dong, Hong-Yu Xu, Jin-Song Shi, Dianhua Jiang, Xin Xu, Lian Li, Zheng-Hong Xu, Yan Geng
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cell Communication and Signaling
Subjects:
Hepatic fibrosis
Cell differentiation
Transforming growth factor-β (TGF-β) signaling
Follistatin like 1 (Fstl1)
microRNA
Online Access:http://link.springer.com/article/10.1186/s12964-020-00610-0

Internet

http://link.springer.com/article/10.1186/s12964-020-00610-0

Similar Items