Biodistribution of adeno-associated virus serotype 9 after intrathecal and intravenous delivery in mouse

Adeno-associated virus serotype 9 (AAV9)-mediated gene transfer has been reported in central nervous system (CNS) and peripheral tissues. The current study compared the pattern of expression of Green Fluorescent Protein (GFP) across the mouse CNS and selected peripheral tissues after intrathecal (i....

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Bibliographic Details
Main Authors: Daniel J. Schuster, Jaclyn A. Dykstra, Maureen eRiedl, Kelley eKitto, Lalitha eBelur, R. Scott eMcIvor, Robert eElde, Carolyn eFairbanks, Lucy eVulchanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Neuroanatomy
Subjects:
CNS
DRG
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00042/full