Naturalistic Spike Trains Drive State-Dependent Homeostatic Plasticity in Superficial Layers of Visual Cortex

Naturalistic Spike Trains Drive State-Dependent Homeostatic Plasticity in Superficial Layers of Visual Cortex

The history of neural activity determines the synaptic plasticity mechanisms employed in the brain. Previous studies report a rapid reduction in the strength of excitatory synapses onto layer 2/3 (L2/3) pyramidal neurons of the primary visual cortex (V1) following two days of dark exposure and subse...

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Bibliographic Details
Main Authors: Varun Chokshi, Bryce D. Grier, Andrew Dykman, Crystal L. Lantz, Ernst Niebur, Elizabeth M. Quinlan, Hey-Kyoung Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
metaplasticity
homeostatic plasticity
synaptic depression
visual experience
mEPSCs
miniature excitatory postsynaptic currents
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.663282/full

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https://www.frontiersin.org/articles/10.3389/fnsyn.2021.663282/full

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