IL-17A+GM-CSF+ Neutrophils Are the Major Infiltrating Cells in Interstitial Lung Disease in an Autoimmune Arthritis Model

IL-17A+GM-CSF+ Neutrophils Are the Major Infiltrating Cells in Interstitial Lung Disease in an Autoimmune Arthritis Model

ObjectiveTo gain a better understanding of the pathogenesis of autoimmune arthritis-associated interstitial lung disease (ILD), we sought to identify the characteristics of lung-infiltrating cells in SKG mice with ILD.MethodsWe injected curdlan in SKG mice at 8 weeks of age, and identified the prese...

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Bibliographic Details
Main Authors: Oh Chan Kwon, Eun-Ju Lee, Eun-Ju Chang, Jeehee Youn, Byeongzu Ghang, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
GM-CSF
IL-17A
neutrophil
autoimmune arthritis
interstitial lung disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01544/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01544/full

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