Conformational Changes in Two Inter-Helical Loops of Mhp1 Membrane Transporter.

Mhp1 is a bacterial secondary transporter with high-resolution crystal structures available for both the outward- and inward-facing conformations. Through molecular dynamics simulations of the ligand-free Mhp1 as well as analysis of its crystal structures, here we show that two inter-helical loops,...

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Bibliographic Details
Main Authors: Hyun Deok Song, Fangqiang Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4505851?pdf=render