Thapsigargin—From Traditional Medicine to Anticancer Drug

Thapsigargin—From Traditional Medicine to Anticancer Drug

A sesquiterpene lactone, thapsigargin, is a phytochemical found in the roots and fruits of Mediterranean plants from <i>Thapsia</i> L. species that have been used for centuries in folk medicine to treat rheumatic pain, lung diseases, and female infertility. More recently thapsigargin was...

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Bibliographic Details
Main Authors: Agata Jaskulska, Anna Ewa Janecka, Katarzyna Gach-Janczak
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
thapsigargin
cytotoxin
anticancer activity
sarcoplasmic/endoplasmic reticulum Ca<sup>2+</sup> ATPase
unfold protein response
apoptosis
Online Access:https://www.mdpi.com/1422-0067/22/1/4

Internet

https://www.mdpi.com/1422-0067/22/1/4

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