Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells

Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells

<i>Background:</i> Interleukin 13 receptor alpha 2 subunit (IL13R&#945;2) is overexpressed in glioblastoma (GBM), metastatic colorectal cancer (CRC) and ovarian cancer (OC). Here, we investigated the IL13R&#945;2 interactome searching for novel targets in cancer invasion and meta...

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Bibliographic Details
Main Authors: Rubén A. Bartolomé, Ángela Martín-Regalado, Marta Jaén, Markella Zannikou, Peng Zhang, Vivian de los Ríos, Irina V. Balyasnikova, J. Ignacio Casal
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
colorectal cancer
egfr
glioblastoma
il13rα2
metastasis
ovarian cancer
ptp1b
src
Online Access:https://www.mdpi.com/2072-6694/12/2/500

Internet

https://www.mdpi.com/2072-6694/12/2/500

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