Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium.

Glutamate-induced cytotoxicity is partially mediated by enhanced oxidative stress. The objectives of the present study are to determine the effects of glutamate on mitochondrial membrane potential, oxygen consumption, mitochondrial dynamics and autophagy regulating factors and to explore the protect...

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Bibliographic Details
Main Authors: Santosh Kumari, Suresh L Mehta, P Andy Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378533?pdf=render