Transcriptional and Microenvironmental Regulation of Lineage Ambiguity in Leukemia

Leukemia is characterized by the uncontrolled production of leukemic cells and impaired normal hematopoiesis. Although the combination of chemotherapies and hematopoietic stem cell transplantation has significantly improved the outcome of leukemia patients, a proportion of patients still suffer from...

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Bibliographic Details
Main Authors: Tianyuan Hu, Rebecca Murdaugh, Daisuke Nakada
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00268/full