TLR-9 Plays a Role in Mycobacterium leprae-Induced Innate Immune Activation of A549 Alveolar Epithelial Cells

TLR-9 Plays a Role in Mycobacterium leprae-Induced Innate Immune Activation of A549 Alveolar Epithelial Cells

The respiratory tract is considered the main port of entry of Mycobacterium leprae, the causative agent of leprosy. However, the great majority of individuals exposed to the leprosy bacillus will never manifest the disease due to their capacity to develop protective immunity. Besides acting as a phy...

Full description

Bibliographic Details
Main Authors: André Alves Dias, Carlos Adriano de Matos e Silva, Camila Oliveira da Silva, Natasha Ribeiro Cardoso Linhares, João Pedro Sousa Santos, Aislan de Carvalho Vivarini, Maria Ângela de Mello Marques, Patrícia Sammarco Rosa, Ulisses Gazos Lopes, Márcia Berrêdo-Pinho, Maria Cristina Vidal Pessolani
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium leprae
Toll-like receptor 9 (TLR-9)
extracellular DNA
histone-like protein (Hlp)
respiratory epithelial cells
innate immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.657449/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.657449/full

Similar Items