Nonmonotonic Dose–Response Curves Occur in Dose Ranges That Are Relevant to Regulatory Decision-Making

Non-monotonic dose response curves (NMDRCs) occur in cells, tissues, animals and human populations in response to nutrients, vitamins, pharmacological compounds, hormones and endocrine disrupting chemicals (EDCs). Yet, regulatory agencies have argued that NMDRCs are not common, are not found for adv...

Full description

Bibliographic Details
Main Authors: Corinne E. Hill, J. P. Myers, Laura N. Vandenberg
Format: Article
Language:English
Published: SAGE Publishing 2018-09-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325818798282