A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis

<p>Abstract</p> <p>Background</p> <p>Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats tha...

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Bibliographic Details
Main Authors: Srinivasan R Sathish, Johns Scott C, Lawrence Roger, Truty Jadwiga, Yin Xin, Handel Tracy M, Fuster Mark M
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/316