Genistein attenuated gastric inflammation and apoptosis in Helicobacter pylori-induced gastropathy in rats

Abstract Background Helicobacter pylori (H. pylori) infection is a major cause of chronic gastritis, peptic ulcer diseases and cancer. Genistein (4′,5,7-trihydroxyisoflavone), a tyrosine-specific-protein kinase inhibitor, has been shown to exert an anti-inflammatory property. The aim of this study w...

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Main Authors: Prasong Siriviriyakul, Duangporn Werawatganon, Nisarat Phetnoo, Kanjana Somanawat, Tanittha Chatsuwan, Naruemon Klaikeaw, Maneerat Chayanupatkul
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-020-01555-x