Application of biomarkers in cancer risk management: evaluation from stochastic clonal evolutionary and dynamic system optimization points of view.

Aside from primary prevention, early detection remains the most effective way to decrease mortality associated with the majority of solid cancers. Previous cancer screening models are largely based on classification of at-risk populations into three conceptually defined groups (normal, cancer withou...

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Bibliographic Details
Main Authors: Xiaohong Li, Patricia L Blount, Thomas L Vaughan, Brian J Reid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3044766?pdf=render