Identification and Characterization of Novel CFTR Potentiators

Identification and Characterization of Novel CFTR Potentiators

There is still a high unmet need for the treatment of most patients with cystic fibrosis (CF). The identification and development of new Cystic Fibrosis Transmembrane conductance Regulator (CFTR) modulators is necessary to achieve higher clinical benefit in patients. In this report we describe the c...

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Bibliographic Details
Main Authors: Maarten Gees, Sara Musch, Steven Van der Plas, Anne-Sophie Wesse, Ann Vandevelde, Katleen Verdonck, Oscar Mammoliti, Tzyh-Chang Hwang, Kathleen Sonck, Pieter Stouten, Andrew M. Swensen, Mia Jans, Jan Van der Schueren, Luc Nelles, Martin Andrews, Katja Conrath
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
CF
CFTR
potentiator
bronchial epithelial cells
electrophysiology
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01221/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01221/full

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