Permutation-based methods for mediation analysis in studies with small sample sizes

Background Mediation analysis can be used to evaluate the effect of an exposure on an outcome acting through an intermediate variable or mediator. For studies with small sample sizes, permutation testing may be useful in evaluating the indirect effect (i.e., the effect of exposure on the outcome thr...

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Bibliographic Details
Main Authors: Miranda E. Kroehl, Sharon Lutz, Brandie D. Wagner
Format: Article
Language:English
Published: PeerJ Inc. 2020-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8246.pdf