PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx.

PML (Promyelocytic Leukemia protein), also known as TRIM19, belongs to the family of tripartite motif (TRIM) proteins. PML is mainly expressed in the nucleus, where it forms dynamic structures known as PML nuclear bodies that recruit many other proteins, such as Sp100 and Daxx. While the role of PML...

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Bibliographic Details
Main Authors: Jacques Dutrieux, Ghizlane Maarifi, Débora M Portilho, Nathalie J Arhel, Mounira K Chelbi-Alix, Sébastien Nisole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005280