Following Ariadne's thread: a new perspective on RBR ubiquitin ligases
<p>Abstract</p> <p>Ubiquitin signaling pathways rely on E3 ligases for effecting the final transfer of ubiquitin from E2 ubiquitin conjugating enzymes to a protein target. Here we re-evaluate the hybrid RING/HECT mechanism used by the E3 family RING-between-RINGs (RBRs) to transfer...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-03-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/10/24 |