A novel LC–MS/MS assay for methylprednisolone in human plasma and its pharmacokinetic application

A novel LC–MS/MS assay for methylprednisolone in human plasma and its pharmacokinetic application

Methylprednisolone is a synthetic glucocorticoid. In our report, the authors proposed a sensitive and selective liquid chromatography/tandem mass spectrometry (LC–MS/MS) assay for the determination of methylprednisolone applying budesonide as internal standard. Liquid–liquid extraction (LLE) having...

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Bibliographic Details
Main Authors: Sridhar Siddiraju, Mercy Lazar Lal Prasanth, Tadiboyina Sirisha
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Methylprednisolone
Human plasma
Method validation
LC–MS/MS
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615000707

Internet

http://www.sciencedirect.com/science/article/pii/S1818087615000707

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