Evaluation of iTRAQ and SWATH-MS for the Quantification of Proteins Associated with Insulin Resistance in Human Duodenal Biopsy Samples.

Insulin resistance (IR) is associated with increased production of triglyceride-rich lipoproteins of intestinal origin. In order to assess whether insulin resistance affects the proteins involved in lipid metabolism, we used two mass spectrometry based quantitative proteomics techniques to compare t...

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Bibliographic Details
Main Authors: Sylvie Bourassa, Frédéric Fournier, Benjamin Nehmé, Isabelle Kelly, André Tremblay, Valéry Lemelin, Benoit Lamarche, Patrick Couture, Arnaud Droit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4423961?pdf=render