Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system

Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system

Bacteria use the type 2 secretion system to secrete enzymes and toxins across the outer membrane to the environment. Here the authors analyse the T2SS pathway in three protist lineages and suggest that the early mitochondrion may have been capable of secreting proteins into the cytosol.

Bibliographic Details
Main Authors: Lenka Horváthová, Vojtěch Žárský, Tomáš Pánek, Romain Derelle, Jan Pyrih, Alžběta Motyčková, Veronika Klápšťová, Martina Vinopalová, Lenka Marková, Luboš Voleman, Vladimír Klimeš, Markéta Petrů, Zuzana Vaitová, Ivan Čepička, Klára Hryzáková, Karel Harant, Michael W. Gray, Mohamed Chami, Ingrid Guilvout, Olivera Francetic, B. Franz Lang, Čestmír Vlček, Anastasios D. Tsaousis, Marek Eliáš, Pavel Doležal
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23046-7

Internet

https://doi.org/10.1038/s41467-021-23046-7

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