CATHEDRAL: a fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures.

We present CATHEDRAL, an iterative protocol for determining the location of previously observed protein folds in novel multidomain protein structures. CATHEDRAL builds on the features of a fast secondary-structure-based method (using graph theory) to locate known folds within a multidomain context a...

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Bibliographic Details
Main Authors: Oliver C Redfern, Andrew Harrison, Tim Dallman, Frances M G Pearl, Christine A Orengo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2098860?pdf=render