Meta-metallation of N,N-dimethylaniline: Contrasting direct sodium-mediated zincation with indirect sodiation-dialkylzinc co-complexation

Meta-metallation of N,N-dimethylaniline: Contrasting direct sodium-mediated zincation with indirect sodiation-dialkylzinc co-complexation

Previously we reported that direct zincation of N,N-dimethylaniline by the mixed-metal zincate reagent 1 ((TMEDA)Na(TMP)(t-Bu)Zn(t-Bu)) surprisingly led to meta-metallation (zincation) of the aniline, as manifested in the crystalline complex 2 ((TMEDA)Na(TMP)(m-C6H4-NMe2)Zn(t-Bu)), and that iodinati...

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Bibliographic Details
Main Authors: David R. Armstrong, Liam Balloch, Eva Hevia, Alan R. Kennedy, Robert E. Mulvey, Charles T. O'Hara, Stuart D. Robertson
Format: Article
Language:English
Published: Beilstein-Institut 2011-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
alkali metal
crystal structure
isomerisation
metallation
zincation
Online Access:https://doi.org/10.3762/bjoc.7.144

Internet

https://doi.org/10.3762/bjoc.7.144

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