Localization of near-infrared labeled antibodies to the central nervous system in experimental autoimmune encephalomyelitis.

Antibodies, including antibodies to the RNA binding protein heterogeneous nuclear ribonucleoprotein A1, have been shown to contribute to the pathogenesis of multiple sclerosis, thus it is important to assess their biological activity using animal models of disease. Near-infrared optical imaging of f...

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Bibliographic Details
Main Authors: Sangmin Lee, Hannah E Salapa, Michael C Levin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212357