Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway
<p>Abstract</p> <p>Background</p> <p>Microglia are the principal cells involved in the innate immune response in the CNS. Activated microglia produce a number of proinflammatory cytokines implicated in neurotoxicity but they also are a major source of anti-inflammatory...
Main Authors: | Tarassishin Leonid, Suh Hyeon-Sook, Lee Sunhee C |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-12-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://www.jneuroinflammation.com/content/8/1/187 |
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