Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

<p>Abstract</p> <p>Background</p> <p>Microglia are the principal cells involved in the innate immune response in the CNS. Activated microglia produce a number of proinflammatory cytokines implicated in neurotoxicity but they also are a major source of anti-inflammatory...

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Bibliographic Details
Main Authors: Tarassishin Leonid, Suh Hyeon-Sook, Lee Sunhee C
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Neuroinflammation
Subjects:
neuroinflammation
neurodegeneration
innate immunity
human
cytokines
chemokines
antiviral genes
microarray
interferon-beta
TLR
Online Access:http://www.jneuroinflammation.com/content/8/1/187

Internet

http://www.jneuroinflammation.com/content/8/1/187

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