Paxillin: a crossroad in pathological cell migration
Abstract Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and signaling molecules involved in cell movement and migration, when phosphorylated on specific Tyr and Ser residues. Upon in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-02-01
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Series: | Journal of Hematology & Oncology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13045-017-0418-y |