Paxillin: a crossroad in pathological cell migration

Abstract Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and signaling molecules involved in cell movement and migration, when phosphorylated on specific Tyr and Ser residues. Upon in...

Full description

Bibliographic Details
Main Authors: Ana María López-Colomé, Irene Lee-Rivera, Regina Benavides-Hidalgo, Edith López
Format: Article
Language:English
Published: BMC 2017-02-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-017-0418-y