Nonlinear Dose–Response Modeling of High-Throughput Screening Data Using an Evolutionary Algorithm

Nonlinear dose–response relationships exist extensively in the cellular, biochemical, and physiologic processes that are affected by varying levels of biological, chemical, or radiation stress. Modeling such responses is a crucial component of toxicity testing and chemical screening. Traditional mod...

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Bibliographic Details
Main Authors: Jun Ma, Eric Bair, Alison Motsinger-Reif
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325820926734