Some variables affecting the characteristics of Eudragit E-sodium alginate polyelectrolyte complex as a tablet matrix for diltiazem hydrochloride

Some variables affecting the characteristics of Eudragit E-sodium alginate polyelectrolyte complex as a tablet matrix for diltiazem hydrochloride

Eudragit E (EE)-sodium alginate (SA) polyelectrolyte complexes (PECs) were prepared at pH 4 and 5.8 using sodium alginate of high (SAH) and low viscosity (SAL). The optimum EE-SA complexation mass ratio was determined using viscosity measurements. Interactions between EE and SA in PECs were characte...

Full description

Bibliographic Details
Main Authors: Yusif Rehab Mohammad, Hashim Irhan Ibrahim Abu, El-Dahan Marwa Salah
Format: Article
Language:English
Published: Sciendo 2014-03-01
Series:Acta Pharmaceutica
Subjects:
polyelectrolyte complex
diltiazem hydrochloride
Eudragit E 100
sodium alginate
viscosity
tablet matrix
Online Access:http://www.degruyter.com/view/j/acph.2014.64.issue-1/acph-2014-0010/acph-2014-0010.xml?format=INT

Internet

http://www.degruyter.com/view/j/acph.2014.64.issue-1/acph-2014-0010/acph-2014-0010.xml?format=INT

Similar Items