Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice.

<h4>Background</h4>No animal models of autism spectrum disorders (ASD) with good construct validity are currently available; using genetic models of pathologies characterized by ASD-like deficits, but with known causes, may be therefore a promising strategy. The Fmr1-KO mouse is an examp...

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Bibliographic Details
Main Authors: Susanna Pietropaolo, Aurélie Guilleminot, Benoît Martin, Francesca R D'Amato, Wim E Crusio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21364941/?tool=EBI